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| Cellular & Molecular Medicine Home News Events Contact Apply Now About Leadership CMM History People Primary Faculty Affiliated Faculty Emeritus Faculty Administrative Staff Post Docs and Research Staff Graduate Students Alumni Graduate Students Education Graduate Program in Molecular Medicine MS Program in Cellular and Molecular Medicine Genetic Counseling MS Program Biomedical Sciences Graduate Certificate Graduate Student Handbook Research Resources Cancer Cell Biology Cardiovascular Biology and Disease Cell Polarity and Intracellular Trafficking Complex Diseases - Biology and Genetics Genome Function Willed Body Program LEADERS Training Our Next Leaders in Biomedical Research DISCOVERY A Thriving Environment for Biomedical Discovery Samantha Harris, PhD Understanding Myosin Binding Protein-C in Health and Disease Ray Runyan, PhD Regulation of Cell Invasion in Development and Cancer Brett Colson, PhD Deciphering the Structural Basis for Muscle Contraction at the Molecular Level Curtis Thorne, PhD Discovering Signals Controlling Cell Fate of Regenerative Tissues Tom Doetschman, PhD Synergistic Activities of TGFbeta Deficiency and the Gut Microbiome in Colon Cancer Greg Rogers, PhD Investigating Mechanisms of Genomic Integrity RESEARCH An Established Leader in Cutting-edge Research Cynthia Miranti, PhD Targeting the Extracellular Matrix and Tumor Microenvironment Julie Ledford, PhD Immunological Roles of Endogenous Lung Proteins Noel Warfel, PhD Modeling the Effects of Hypoxia on Cancer Cells and Tumor Angiogenesis Darren Cusanovich, PhD Understanding How the Genome Regulates Diverse Cell Types in Development and Disease Jared Churko, PhD Informatics to Understand Cardiovascular Development and Disease Mechanisms Casey Romanoski, PhD Systems Genetics Approaches to Identify Mechanisms of Complex Diseases Cardiovascular Biology and Diseases Cell Polarity and Intracellular Trafficking Cancer Cell Biology Complex Diseases Biology and Genetics Genome Function Home Message from the Chair The mission of the Department of Cellular and Molecular Medicine (CMM) is to provide pre- and post-doctoral, medical and graduate education in an interdisciplinary environment through research activities, to advance knowledge of biological structure as related to function and disease from the molecular level to the whole organism. Read More Graduate Programs Molecular Medicine PhD Program Cellular & Molecular Medicine MS Program Biomedical Certificate Program Graduate Program in Genetic Counseling See All CMM Publications Announcements Dr. Darnell receives two College of Medicine Outstanding Teaching Awards (February 5, 2020) Professor Diana Darnell, PhD has received two 2020 College of Medicine Faculty Teaching Awards: Outstanding Teacher in a Block, Preclerkship phase and Outstanding Use of Educational Technology . She will be honored for these accomplishments in March at the 40th Annual Faculty Teaching Awards Ceremony, presented by the Academy of Medical Education Scholars (AMES), an organization that recognizes the College’s most outstanding educators. Dr. Gregorio elected as 2020 AACBNC councilor (January 29, 2020) Professor and Department Head Carol Gregorio, PhD was recently elected to the position of Councilor for the Association of Anatomy, Cell Biology, and Neurobiology Chairpersons. This organization of academic departmental leaders provides advocacy in the biomedical sciences and represent the interests of investigators working within these disciplines to develop policy, identify and address emerging issues, and share expertise for the improvement of academic medicine and basic biomedical science. Rogers Lab publishes organellogenesis study in the Journal of Cell Biology (December 17, 2019) In a new study of organelle biogenesis from the laboratory of Gregory Rogers, PhD , former CMM student and postdoc Tiffany McLamarrah and colleagues characterize an early step in centriole duplication. They show that Polo-like kinase hyperphosphorylates the assembly factor Ana2, which increases the affinity of Ana2 for the G-box domain of Sas4, promoting Ana2’s accumulation at the procentriole and, consequently, daughter centriole formation. PMID: 31841145 CMM Master’s Student Receives 2019 Centennial Achievement Award (December 3, 2019) Michelle Ennabe , CMM Master’s Student, is one of three Masters Awardees of this year’s prestigious Centennial Achievement Award. Founded in 1987, this honor recognizes graduating students who demonstrate outstanding academic achievement and contributions to community and family despite facing challenging obstacles along the way. Read more here. Mouneimne Lab publishes mechanosensing study in Journal of Cell Biology (October 14, 2019) In this newest study from the laboratory of Gus Mouneimne, PhD , recently-graduated CMM student Julieann Puleo and colleagues discovered that EVL, the Ena/VASP protein, is crucial for actin polymerization at focal adhesions (FAs). Importantly, they determined that EVL-mediated FA actin polymerization regulates FA maturation and mechanosensing, which are significant steps in mechanically-directed motility and durotactic invasion. This work is a significant contribution to our understanding of how cells interact with their microenvironment in normal and pathological contexts. PMID: 31594807 Dr. Vercelli’s research mentioned in the Washington Post (September 30, 2019) We are (fortunately) not alone. Microbes should no longer be seen as foes that need to be eliminated at all costs. Work from Donata Vercelli, PhD ’s laboratory recently featured in the Washington Post shows that living in traditional farming environments means living in a place that is extremely rich in microbes — the right microbes that our immune system has evolved to live with and learn from. The constellation of organisms found in soil and on farm animals programs how a child responds to allergens throughout her lifetime. This programming likely starts in utero and continues to shape the immune system during the first few years of life. Read more here. Upcoming Events Feb 13 CMM Seminar Series: Michael Gotthardt, PhD Thursday 12:00pm to 1:00pm Seminar Speaker: Michael Gotthardt, PhD, Max Delbrück Center for Molecular Medicine Talk title: Of mice, grizzly bears and men: A phenomics approach to skeletal muscle function and disease HSIB 880 Feb 14 Sarver Heart Center Grand Rounds Friday 12:00pm Speaker: Dr. Brahmajee K Nallamothu MD, Professor, University of Michigan Sarver Heart Center 4137 Feb 19 Genetics & Genomics Grand Rounds Wednesday 4:00pm "Inherited Risk Assessment of Cancer and other common diseases in clinic: it takes three to do it right" with Jianfeng Xu, DrPH Feb 20 CMM Seminar Series: Cancelled Thursday 12:00pm to 1:00pm Student Seminar Speaker: Carol Gregorio. PhD HISB 880 Feb 20 Introduction to Safe Laboratory Practices Thursday 2:00pm to 3:30pm Facilitators: Dr. Kathleen Kennedy, Environmental Health & Safety Manager - TGen ✦ Dr. Jennifer Jeung, Laboratory Operations Manager, COM—P ✦ Dr. Ron Hammer, Co-director - Clinical Translational Sciences Tucson: Health Sciences Innovation Building, Room 531 Phoenix: Biomedical Sciences Partnership Building, Room E112 more Download Events Spotlight Drs. Julie Ledford, PhD (left) and Monica Kraft, MD (right) win the $10,000 prize during UA Research Day’s ‘Shark Tank’ Event for their pitch on a new, inhaled therapeutic for the treatment of asthma and potentially even COPD, cystic fibrosis and pneumonia. UA College of Medicine Department of Cellular & Molecular Medicine 1501 N. Campbell Avenue PO Box 245044 Tucson Arizona 85724-5044 Tel: (520) 626-6084 | Fax: (520) 626-2097 | Admin College of Medicine - Tucson The University of Arizona is an EEO/AA - M/W/D/V Employer. 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